Pages

Showing posts with label Anesthesia Side Effects. Show all posts
Showing posts with label Anesthesia Side Effects. Show all posts

Friday, April 1, 2016

NEUROTOXICITY OF ANESTHETIC AGENTS IN LONG-TERM


๐Ÿ”นHalothane and Isoflurane: Amyloidogenic properties

๐Ÿ”นIsoflurane : Behavioural changes, apoptosis (Sevo lacks this)

๐Ÿ”นNitrous oxide: Dose dependent and paradoxical protective and neurotoxic effects 

๐Ÿ”นOpioids @ moderate to high dose: Brain hyper metabolism and damage; Remifentanil doubtful role in genesis of Alzheimer's disease

(Acta Rad, CJA, Proct Natl Acad Sci, Anesth, Lancet)