⌛️Etomidate is an imidazole derivative
⌛️It has higher incidence of PONV than other induction agents
⌛️It causes pain on injection
⌛️It can trigger porphyric crisis, in susceptible individuals
⌛️The REVERSIBLE BLOCKADE of the adrenocortical enzymes 11ฮฒ -hydroxylase and 17ฮฑ-hydroxylase, reduces BOTH corticosteroid and mineralocorticoid synthesis and the effect LASTS FOR 3–6 hours after a bolus dose.
⌛️The effect of a bolus of etomidate is terminated by redistribution of drug to peripheral tissues
⌛️The standard dose for induction of anaesthesia is 0.3 mg/ kg
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