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Sunday, November 8, 2015

ANESTHESIA IMPLICATIONS IN MYESTHENIA GRAVIS

 

No priming/ precurarization with NMBA
Can cause airway obstruction during induction

Less efficacy of neostigmine as patient is on long term pyridostigmine

High risk of phase 2 block with succinyl choline

Sevoflurane better to use <1 mac; >1 MAC can produce significant NMB

In fact, we can avoid nmba fully with sevoflurane

Better to monitor tof even with sevo alone

Steroids reduce dose requirement of nmba

If pulmonary reserve is poor ...consider plasmapheresis

Whether to continue anticholinesterase, d/w neurologist

Regional anesthesia is better

PAIN CAN PRECIPITATE MYASTHENIC CRISIS: So give good postoperative analgesia

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