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Monday, November 30, 2015

THE DICTATORS OF NIGHT👑💤; NREM Vs REM COMPARISON↔️



🎭Cerebral blood flow is reduced in NREM , whereas it is markedly increased in REM

🎭Sleep walks and night terrors occur in NREM; whereas dreams occur in REM

🎭Muscle tone, especially, Upper airway muscle tone is significantly reduced in REM. 

🎭DO YOU KNOW❓The only somatic muscles working in REM are the extraocular muscles and diaphragm❗️❗️

🎭There is a shift in the autonomic nervous system in sleep, with parasympathetic nervous system predominance in NREM and especially in REM

🎭NREM is organized into four stages. In a typical night of adult sleep, Stage 1 will comprise up to 5% of total sleep, Stage 2 up to 50%, SWS ( Slow Wave Sleep= Stage 3+4) up to 20%, and REM up to 25%

🎭SWS is predominately experienced in the first third of sleep and REM in the last half of sleep. Achieving SWS has neuroendocrine significance.

〰NEW INSIGHTS〰

😴Unlike propofol, sevoflurane anesthesia has differential effects on NREM and REM sleep homeostasis. (i.e.  Total sleep deprivation resulted in significantly increased NREM and REM sleep for 12-h postdeprivation. Sevoflurane exposure after deprivation eliminated the homeostatic increase in NREM sleep and produced a significant decrease in the NREM sleep δ power during the postanesthetic period, indicating a complete recovery from the effects of deprivation)

These data confirm the previous hypothesis that inhalational agents do not satisfy the homeostatic need for REM sleep, and that the relationship between sleep and anesthesia is likely to be agent and state specific.

(Pal D, Lipinski WJ, Walker AJ, Turner AM, Mashour GA
Anesthesiology [2011, 114(2):302-310)]

😴Help your patient in getting a quality sleep on preoperative day❗️

Sleep Loss and REM Sleep Loss are Hyperalgesic
Timothy Roehrs, Maren Hyde, Brandi Blaisdell, M Mark Greenwald, Thomas Roth (SLEEP, Vol. 29, No.2, 2006)

#sleep ,#nremsleep , #rem , #SleepClinic , #SleepStudy , #AnaesthesiaSleep ,#osas ,#cpap ,#brain , #SWS

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